Melatonin Dosage Calculator
Find recommended melatonin dose by indication and calculate tablets, liquid volume, or spray applications for your therapy duration.
What Is Melatonin?
Melatonin is a hormone produced by the pineal gland that regulates the sleep-wake cycle (circadian rhythm). Over-the-counter melatonin supplements are widely used for insomnia, jet lag, shift work, and certain medical conditions. Doses vary by indication, age, and formulation. This calculator provides evidence-based dose ranges and timing for common uses. For broader sleep assessment, try the Epworth Sleepiness Scale Calculator and the Sleep Cycle Calculator.
Melatonin Doses by Indication
For trouble falling asleep, typical doses range from 0.3 to 5 mg taken about 1 hour before bedtime; 3 mg is a common starting dose. Jet lag (eastbound travel) often uses 0.5 to 5 mg before bedtime for 2 days before departure and 4 days after arrival. Westbound jet lag may require dosing for 4 days after arrival only. Insomnia in blind individuals uses a lower dose of 0.5 mg around 9 to 10 PM. Beta-blocker-associated insomnia may respond to 2.5 mg nightly for up to 4 weeks. Endometriosis trials have used 10 mg daily for up to 8 weeks under medical supervision.
Formulations and Safety
Melatonin comes as tablets, capsules, liquids, sprays, and dissolving strips. Lower doses (0.3 to 1 mg) may be as effective as higher doses for sleep onset with fewer next-day effects. Take melatonin 30 to 60 minutes before desired sleep. Side effects can include daytime drowsiness, headache, and vivid dreams. Melatonin is generally well tolerated short term but long-term safety data are limited. Consult a healthcare provider before use in children, during pregnancy, or with other medications.
Frequently Asked Questions
How much melatonin should I take for sleep?
Most adults start with 1 to 3 mg taken 30 to 60 minutes before bedtime. Doses from 0.3 to 5 mg are commonly used. Higher doses do not always work better and may cause more morning grogginess.
What melatonin dose helps jet lag?
For eastbound travel, 0.5 to 5 mg before bedtime starting 2 days before the flight and continuing 4 days after arrival is commonly recommended. Westbound travel typically requires dosing for 4 days after arrival only.
Is melatonin safe for long-term use?
Short-term use up to 3 months appears safe for most adults. Long-term safety data are limited. Use the lowest effective dose and discuss ongoing use with your doctor, especially if sleep problems persist beyond a few weeks.
Can I take melatonin with other medications?
Melatonin may interact with anticoagulants, immunosuppressants, diabetes medications, and blood pressure drugs. It can also enhance sedation from other sleep aids. Tell your pharmacist about all medications and supplements before starting melatonin.
What is the best time to take melatonin?
Take melatonin 30 to 60 minutes before your intended sleep time. For circadian rhythm disorders in blind individuals, dosing around 9 to 10 PM aligns with desired sleep onset regardless of environmental light cues.