Carboplatin Calculator

Carboplatin Dosing Overview

Carboplatin is dosed by area under the curve (AUC) rather than by body surface area alone. The Calvert formula links target AUC to renal function. This calculator uses Cockcroft-Gault creatinine clearance and caps GFR at 125 mL/min for the maximum dose estimate.

Formulas

$$\text{Cockcroft-Gault (male)} = \frac{(140 - age) \times weight}{72 \times SCr}$$

$$\text{Cockcroft-Gault (female)} = \frac{(140 - age) \times weight \times 0.85}{72 \times SCr}$$

$$\text{Calvert dose (mg)} = AUC \times (GFR + 25)$$

Age is in years, weight in kg, and serum creatinine (SCr) in mg/dL. GFR is capped at 125 mL/min when calculating the maximum dose note.

Clinical Notes

Institutional protocols, actual body weight versus ideal weight, and alternative renal estimates may change the final prescribed dose. Always confirm with oncology pharmacy and local guidelines.