Isotretinoin Dose Calculator

Isotretinoin Therapy Overview

Isotretinoin (Accutane) is an oral retinoid used for severe nodular or treatment-resistant acne. Courses are planned around a cumulative dose per body weight, typically 120 to 150 mg/kg over several months. This calculator estimates cumulative dose, daily dose, and treatment duration from weight and your chosen planning mode. For general dosing math, see the Dosage Calculator.

Cumulative Dose Targets

Dermatology guidelines often aim for roughly 120 to 150 mg/kg total exposure to reduce relapse risk. The mean target of 135 mg/kg is a common planning midpoint. Daily dose is usually started low and may increase toward about 1 mg/kg per day under specialist supervision.

Monitoring and Safety

Isotretinoin requires pregnancy prevention, periodic blood tests for lipids and liver enzymes, and monitoring for mood changes and dryness. Never adjust dose without your dermatologist. This tool supports education only and does not replace prescribed regimens.