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CDAI Calculator

Calculate Crohn Disease Activity Index from symptoms, labs, and complications with clinical interpretation.

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What Is the Crohn Disease Activity Index?

The Crohn Disease Activity Index (CDAI) quantifies inflammatory bowel disease activity from symptoms, physical findings, and laboratory data collected over seven days. It helps track response to therapy and research endpoints. Related tools: CAGE Questionnaire Calculator and Braden Score Calculator.

Score Components

CDAI combines stool frequency, abdominal pain, general well-being, complications, antidiarrheal use, abdominal mass, hematocrit deficit, and weight loss relative to ideal weight. Each domain carries a fixed multiplier reflecting its clinical weight in the original validation study.

$$\text{CDAI} = \sum \text{weighted clinical variables}$$

Interpretation Bands

  • Below 150: remission
  • 150 to 450: active Crohn disease
  • Above 450: severe disease

Clinical Use

Gastroenterologists use CDAI in trials and sometimes in practice to document disease course. It requires reliable patient diaries and consistent examiner assessment of abdominal mass and complications.

Frequently Asked Questions

What counts as a liquid stool for CDAI?

Very soft or watery stools reported by the patient over the prior seven days, as defined in the original CDAI protocol.

Why does antidiarrheal use subtract points?

Loperamide or diphenoxylate can mask symptoms. The index penalizes masked activity by subtracting 30 points when these drugs were used.

How is hematocrit scored?

Points increase when hematocrit falls below sex-specific reference targets, reflecting anemia from chronic inflammation.

Is CDAI used for ulcerative colitis?

No. Ulcerative colitis uses other indices such as partial Mayo score or Truelove and Witts criteria.

How often should CDAI be calculated?

It is most meaningful when symptoms and labs reflect a consistent seven-day window, often at follow-up visits or study time points.