Michaelis Menten Equation Calculator

Michaelis-Menten Equation Calculator

The Michaelis-Menten model describes the rate of an enzyme-catalyzed reaction as substrate concentration changes. It is central to biochemistry and enzyme kinetics.

$$V = \frac{V_{\max}[S]}{[S] + K_m}$$

where $V$ is the reaction rate, $V_{\max}$ is the maximum rate at saturating substrate, $[S]$ is substrate concentration, and $K_m$ is the Michaelis constant. When $[S] = K_m$, the reaction rate is half of $V_{\max}$.

This calculator solves for any one of the four variables when the other three are known. Rearranged forms include $V_{\max} = V([S]+K_m)/[S]$ and $K_m = [S](V_{\max}-V)/V$.

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