Lung Cancer Risk Calculator
Estimate 6-year and 16-year lung cancer risk in smokers using the HUNT study prediction model.
Lung Cancer Risk in Smokers
This calculator estimates 6-year and 16-year lung cancer risk in current and former smokers using prediction models from the HUNT study (Markaki et al.). It incorporates age, sex, BMI, smoking history, occupational exposure, and daily cough to produce individualized risk estimates.
How Risk Is Calculated
The model computes log-odds from weighted factors including sex, age, pack-years, cigarettes per day, years since quitting, BMI, occupational radon or dust exposure hours, and chronic cough. Pack-years equal (cigarettes per day ÷ 20) × years smoked. BMI is weight in kg divided by height in meters squared. Probability is converted from log-odds using 100 ÷ (1 + e−log odds).
Screening Thresholds
The HUNT model uses a 6-year risk threshold of 0.64% and a 16-year risk threshold of 1.75% for identifying individuals who may benefit from low-dose CT lung cancer screening. Results above these thresholds warrant discussion with a healthcare provider about screening eligibility per current guidelines.
Frequently Asked Questions
Who can use this lung cancer risk calculator?
The HUNT model is validated for current and former smokers aged 18 and older. It is not intended for never-smokers or non-smoking populations.
What are pack-years?
Pack-years measure cumulative smoking exposure: (cigarettes per day ÷ 20) × total years smoked. For example, 20 cigarettes daily for 30 years equals 30 pack-years.
What do the 0.64% and 1.75% thresholds mean?
These are the 6-year and 16-year risk cutoffs from the HUNT study used to identify smokers who may qualify for lung cancer screening with low-dose CT.
Why is cigarettes per day limited to 2–35?
The HUNT prediction model was developed and validated within this smoking intensity range. Values outside this range may not produce reliable estimates.
Does occupational exposure affect lung cancer risk?
Yes. Hours per week of occupational exposure to substances such as radon or dust are included in the model. Zero exposure is handled with a minimum floor value in the logarithmic term.