HOMA IR Calculator
Calculate HOMA-IR and QUICKI index from fasting glucose and insulin to assess insulin resistance.
What Is HOMA-IR?
HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) estimates insulin resistance from a single fasting blood draw. It combines fasting glucose and fasting insulin into one index. Clinicians use it alongside A1c and fasting glucose when evaluating metabolic syndrome, prediabetes, and type 2 diabetes risk. Pair results with the HbA1c Calculator and Blood Sugar Converter to compare long-term and point-in-time glucose markers.
How HOMA-IR Is Calculated
The formula is (fasting insulin × fasting glucose) ÷ 405 when glucose is in mg/dL, or ÷ 22.5 when glucose is in mmol/L. Insulin must be in mU/L. Both values should come from the same fasting sample after at least 8 hours without food. This calculator also reports QUICKI, a related insulin sensitivity index derived from the same inputs.
Interpreting Your Result
Values below 1.5 often suggest normal sensitivity. Scores from 1.5 to 2.0 are borderline. Scores above 2.0 raise concern for insulin resistance, and values above 2.5 strongly suggest it. HOMA-IR is a screening aid, not a diagnosis. Diet, weight, activity, and medications all influence results. For nutrition planning, see the Macro Calculator.
Frequently Asked Questions
What fasting glucose and insulin values do I need?
Use fasting glucose (mg/dL or mmol/L) and fasting insulin in mU/L from the same blood draw after at least 8 hours without food. Mixed units are supported; the calculator applies the correct divisor automatically.
What HOMA-IR score suggests insulin resistance?
Scores above 2.0 may suggest insulin resistance, and scores above 2.5 strongly suggest it. Cutoffs vary by population and lab, so always interpret results with a healthcare provider.
What is the QUICKI index shown alongside HOMA-IR?
QUICKI (Quantitative Insulin Sensitivity Check Index) uses the same fasting glucose and insulin values. Lower QUICKI values indicate reduced insulin sensitivity. Values below 0.45 may suggest resistance; below 0.30 may suggest diabetes or marked resistance.
Can HOMA-IR diagnose diabetes?
No. HOMA-IR estimates insulin resistance from fasting labs. A formal diabetes diagnosis requires clinical criteria such as fasting glucose, oral glucose tolerance testing, or HbA1c interpreted by a provider.
Why do glucose units change the formula?
The original HOMA-IR equation was derived for mg/dL glucose. When glucose is entered in mmol/L, the divisor changes to 22.5 so the index stays equivalent. Insulin remains in mU/L in both cases.
Related Tools
Cardiac Output Calculator
Dijkstra's Shortest Path Calculator
Retention Ratio Calculator
Business Loan Calculator
Percentage Decrease Calculator
Even Numbers Generator
Linear Inches Calculator
Octal to Base64 Converter
FFMI Calculator
Amps To Watts Calculator
Black Friday Calculator
Christmas Day Finder
Time Duration Calculator
Image Color Palette Generator
Albumin Globulin Ratio Calculator
Opportunity Cost
Count Hours Calculator
Rental Commission Calculator
Permeameter Calculator
Convolution Calculator